However, vaccinal antibody response at 6 week-old, was significantly higher in garlic group A (2.8☐.8) than in no-garlic group F (1.8☑.8) in the absence of infection. Results: The two infected garlic groups B (non-vaccinated) and C (vaccinated) had lower scores for clinical signs (23 and 12 points, respectively) but higher mortality rates (30% and 25%, respectively) than their no-garlic controls (E 27 points, 11.8% and D 21 points, 0%, respectively). Data generated was analysed using descriptive statistics, ANOVA and Duncan's multiple comparison tests (P<0.05). Virus antibody titre in serum was assayed at 1 day-old, 4 and 6 weeks-old using quantitative agar gel immunodiffusion test. Histopathological lesions in bursae of Fabricius were recorded. Clinical signs, mortality and gross pathological lesions were scored. At 8 and 18 days of age groups A, C, D and F were administered IBD vaccine and groups B, C, D and E were infected with 1LD50 IBD virus (10-3.4 in 0.08ml PBS) via conjuctival instillation at 4 week-old. Groups A, B and C had 0.125% of garlic-meal in feed. Materials and methods: Day-old broilers (102) were separated into 6 groups A-F of 17 each. Objective: This study was carried out to evaluate the effect of garlic (Allium sativum) with its immunomodulatory activity, on the susceptibility of broilers to infectious bursal disease, being an immunosuppressive disease.
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